Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6065525 | Journal of Allergy and Clinical Immunology | 2015 | 18 Pages |
Abstract
Both pathologic and genetic approaches support a role for IL1RL1 in severe asthma, as well as TH2-lke asthma, suggesting that targeting this pathway may have therapeutic benefits.
Keywords
ICSAEC3-amino-9-ethylcarbazoleLTRATH2 inflammationCLCA1FeNOATSOCsBALSARPGAPDHST2LIL1RL1sST2AsthmaLeukotriene receptor antagonistAliAmerican Thoracic SocietySevere Asthma Research ProgramFraction of exhaled nitric oxidebody mass indexBMIbronchoalveolar lavageair-liquid InterfaceSingle nucleotide polymorphismsSingle nucleotide polymorphismSNPInhaled corticosteroidsoral corticosteroidsglyceraldehyde-3-phosphate dehydrogenase
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Authors
Russell S. MD, PhD, Crystal E. BS, Gregory A. PhD, Deborah A. PhD, Eugene R. MD, Sally E. MD,