Distinct parameters of the basophil activation test reflect the severity and threshold of allergic reactions to peanut

Article ID	Journal	Published Year	Pages	File Type
6065557	Journal of Allergy and Clinical Immunology	2015	8 Pages	PDF

Abstract

Basophil reactivity is associated with severity and basophil sensitivity is associated with the threshold of allergic reactions to peanut. CD63 peanut/anti-IgE and CD-sens values can be used to estimate the severity and threshold of allergic reactions during OFCs.

Keywords

Peanut extract CD63 CD203c EC50 LEAP SPT Basophil activation test Threshold peanut allergy Peanut Skin prick test Sensitivity double-blind Severity half maximal effective concentration placebo-controlled food challenge Learning Early About Peanut Allergy

Related Topics

Life Sciences Immunology and Microbiology Immunology

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Distinct parameters of the basophil activation test reflect the severity and threshold of allergic reactions to peanut

Authors

Alexandra F. MD, MSc, George FRCPCH, Abdel PhD, Suzana MD, Alick PhD, Victor PhD, Gideon MD, FRCPCH,