| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6066480 | Journal of Allergy and Clinical Immunology | 2013 | 16 Pages |
Abstract
Heterozygous mutations in STAT3 lead to reduced numbers of circulating TFH-like cells, a finding that might account (at least in part) for the observed defect in antibody production.
Keywords
TFHinducible costimulator ligandICOSLIL-21 receptorIL-21RB-cell lymphoma 6L-selectinCD62LICOSNaïve B cellsCD40LBCL6SEBCSRPD-1STAT3Staphylococcal enterotoxin BHumanT cellsCell activationCD40 ligandsignal transducer and activator of transcription 3Germinal centerProgrammed death 1class-switch recombinationInducible costimulator
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Authors
Fabienne PhD, Capucine MD, PhD, Sven PhD, Alain MD, PhD, Anne MD, PhD,