| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6066485 | Journal of Allergy and Clinical Immunology | 2013 | 10 Pages |
Abstract
The present study delineates a number of novel proteins, TLR3-related pathways, and cellular phenotypes that may help elucidate the genetic basis of childhood HSE. Furthermore, our results reveal superoxide dismutase 2 as a potential therapeutic target for amelioration of the neurologic sequelae caused by HSE.
Keywords
ppifHerpes simplex virus 1 (HSV-1)HSV-1HSETLR3SOD2Herpes simplex virus encephalitisIFNstable isotope labeling of amino acids in cell cultureCNSSuperoxide dismutase 2central nervous systemSILACMass spectrometryFibroblastintercellular adhesion molecule-1Herpes simplex virus 1Proteomicspoly(I:C)Toll-like receptor 3
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Rebeca PhD, Claire PhD, Mark BSc, Matthew W.B. PhD, Lazaro BSc, Vanessa PhD, Laurent MD, PhD, Shen-Ying MD, PhD, Jean-Laurent MD, PhD, Jasminka PhD,