| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6066643 | Journal of Allergy and Clinical Immunology | 2012 | 20 Pages |
Abstract
A defective epithelial barrier was found in patients with CRS with nasal polyps along with a decreased expression of TJ proteins. The disruption of epithelial integrity by IFN-γ and IL-4 in vitro indicates a possible role for these proinflammatory cytokines in the pathogenesis of patients with CRS.
Keywords
MMPCRSwNPECPCRSsNPCRSFITCTight junctiontight junctionsAliHSECTERChronic rhinosinusitis with nasal polypsChronic rhinosinusitis without nasal polypsChronic rhinosinusitisCytokinesChronic sinusitiszonula occludensOccludinfluorescein isothiocyanatematrix metalloproteinaseTransepithelial resistanceRegulationair-liquid InterfaceEosinophil cationic proteinclaudin
Related Topics
Life Sciences
Immunology and Microbiology
Immunology
Authors
Michael B. MD, Paulina MSc, Thomas MD, David MD, Angela MSc, Kerstin MSc, Jeannette I. BSc, Cezmi A. MD,