| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6066677 | Journal of Allergy and Clinical Immunology | 2012 | 14 Pages |
Abstract
These data reveal a hitherto unrecognized role of mTOR signaling in IL-33-driven, ILC-dependent inflammation in vivo and suggest that manipulation of this pathway might represent a target for therapeutic intervention for airway inflammation.
Keywords
IL-33TSLPTh2RPS6ICOSPI3KS6K1ILCBALAPCTCrAHRAsthmaallophycocyaninRapamycininnate lymphoid cellInnate lymphoid cellsphycoerythrinphosphoinositide 3-kinasebronchoalveolar lavageThymic stromal lymphopoietinLinwild-typemammalian target of rapamycinAirway hyperresponsivenessRibosomal protein S6Inducible costimulatorT-cell receptor
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Authors
Robert J. PhD, Ananda S. MBChB, Anne-Gaelle PhD, Calum C. BSc, Neil C. MD, Foo Y. PhD,