| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6066685 | Journal of Allergy and Clinical Immunology | 2012 | 15 Pages |
Abstract
These findings suggest that RSV can use an innate antiviral signaling pathway to drive a potentially nonproductive immune response and has important implications for the role of TSLP in viral immune responses in general.
Keywords
Bronchial epithelial growth mediumTLRRSVAECDulbecco Modified Eagle MediumRIG-IIRF-3TSLPTh2BEGMIKKβIPS-1NF-κBMEFBECDMEMAHRMOISmall interfering RNAsiRNAAsthmaperiodic acid–SchiffAlichromatin immunoprecipitationHAUEpitheliumToll-like receptorair–liquid interfaceBronchial epithelial cellairway epithelial cellInterferon regulatory factor 3dominant-negativenuclear factor-κBThymic stromal lymphopoietinmouse embryonic fibroblastknockoutPASwild-typeplaque-forming unitSendai virusRhinovirusRespiratory syncytial virusAirway hyperresponsivenesspfuSeVmultiplicity of infectionCHiP
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Authors
Hai-Chon PhD, Mark B. PhD, Yueh-Ming PhD, Aaron BS, Michael PhD, Jason S. MD, Nicholas W. PhD, Steven F. PhD,