| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6066786 | Journal of Allergy and Clinical Immunology | 2012 | 15 Pages |
Abstract
Complete filaggrin deficiency led to altered barrier integrity and enhanced sensitization, which are important factors in early-phase atopic dermatitis. Flgâ/â mice should provide a valuable tool to further explore additional factors the dysfunction of which leads to uncontrolled inflammation in patients with atopic diseases.
Keywords
TEWLichthyosis vulgarisDNFBFLGOVANMFCHSSPF1-fluoro-2,4-dinitrobenzenestratum granulosumTransepidermal water lossOvalbuminTembarrier functionContact hypersensitivityAtopic dermatitisDIAnatural moisturizing factorfilaggrinStratum corneumUTR یا untranslated regions untranslated regionTransmission electron microscopyTape strippingspecific pathogen free
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Authors
Hiroshi MD, Keisuke MD, PhD, Akiharu MD, PhD, Tsuyoshi PhD, Atsushi DVM, PhD, Hideaki PhD, Taketo MD, PhD, Masayuki MD, PhD,