Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6067112 | Journal of Allergy and Clinical Immunology | 2011 | 15 Pages |
Abstract
These results reveal a novel mechanism of action of IVIg in achieving a therapeutic effect in autoimmune and allergic diseases, in which TH17 cells play a key modulatory role in sustaining the chronic inflammatory response. Our results also suggest a reciprocal regulation of TH17 and regulatory T-cell populations by IVIg.
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Authors
Mohan S. DVM, Janakiraman PhD, Pushpa MSc, Sebastien PhD, Srini V. DVM, PhD, Jagadeesh DVM, PhD,