Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6067200 | Journal of Allergy and Clinical Immunology | 2011 | 9 Pages |
Abstract
The K+ channel KCa3.1 plays a key role in human fibrocyte migration. Currently available KCa3.1-channel blockers might therefore attenuate tissue fibrosis and remodeling in patients with diseases such as idiopathic pulmonary fibrosis and asthma through the inhibition of fibrocyte recruitment.
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Authors
Glenn PhD, Shailendra R. PhD, S. Mark PhD, Camille BSc, Ruth PhD, Chris E. PhD, Peter DM,