| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6067454 | Journal of Allergy and Clinical Immunology | 2010 | 18 Pages |
Abstract
We demonstrated, using both genetic and functional analyses, that EP3 could be a key player in the pathogenesis of SJS/TEN accompanied by ocular complications.
Keywords
PGE2SJSTLR3EP3MAFGAPDHNSAIDFDRconjunctival epitheliumnonsteroidal anti-inflammatory drugtenStevens-Johnson syndromeLinkage disequilibriumminor allele frequencyGenome-wide association studyGWASfalse discovery rateToxic epidermal necrolysisProstaglandin E2Single nucleotide polymorphismSNPquality controlToll-like receptor 3
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Authors
Mayumi MD, PhD, Chie MD, PhD, Masakazu PhD, Takazumi PhD, Tomohito MD, PhD, Yuichi Tokuda, Masahiro Fuwa, Tsutomu MD, PhD, Norihiko MD, PhD, Kei MD, PhD, Shigeru MD, PhD,