Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6067572 | Journal of Allergy and Clinical Immunology | 2010 | 20 Pages |
Abstract
SR-AI/II targets AGE-OVA to the MHC class II loading pathway in mDCs, leading to an enhanced CD4+ T-cell activation. The Maillard reaction might thus play an important role in the T-cell immunogenicity of food allergens.
Keywords
CMLNε-carboxymethyl-lysinereceptor for AGEsCFSERAGEMDCAPCOVACelFITCFood allergenFood allergyantigen-presenting cellOvalbuminDendritic cellDendritic cellsMyeloid dendritic cellAgefluorescein isothiocyanateMaillard reactionadvanced glycation end productcarboxyfluorescein succinimidyl esterGlycolaldehydeMannose receptorMacrophage scavenger receptor
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Authors
Anne BSc, Sven PhD, Stephan PhD, Zoe PhD, Ryoji PhD, Anne BSc, Yasuhiko MD, PhD, Hiroshi MD, PhD, Thomas PhD, Christian MD, Ulrich PhD, Stefan PhD, Masako PhD,