Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6068040 | Journal of Allergy and Clinical Immunology | 2009 | 19 Pages |
Abstract
Sensitivity to multiple allergens leads to chronic asthma in mice. Multiple allergens synergize in dendritic cell signaling and T-cell stimulation that allows escape from the single allergen-associated tolerance development.
Keywords
GTIAHRFOXP3RAWHTIERKMCHOVADRAPhosphorylated ERKMAPKChronic asthmainflammationOvalbuminAirway hyperreactivityToleranceforkhead box P3Dendritic cellsAEHTissue resistanceAirway resistanceMousemitogen-activated protein kinasePERKreduced nicotinamide adenine dinucleotide phosphateTissue elasticityextracellular signal-regulated kinase
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Authors
Nicholas BS, M. Zunayet MD, Qiaoling MD, Magdalena M. MD, PhD, Sadee PhD, Lei PhD, Rafeul MD, PhD,