Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6068607 | The Journal of Allergy and Clinical Immunology: In Practice | 2014 | 4 Pages |
Abstract
We recommend measurement of 24-hour urine 11β-PGF2α and serum tryptase levels of patients with symptoms suggestive of MCAS. Measurement of 24-hour urine 11β-PGF2α and serum tryptase levels can help avoid misdiagnosis and overinterpretation of MCAS symptoms in clinical practice. Given that an elevation of 24-hour urine N-MH level was found only in 2 patients, measurement of this mediator may be less helpful in diagnosing MCAS. We recommend aspirin therapy for patients with MCAS and with elevated 24-hour urine 11β-PGF2α levels.
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Authors
Anupama MD, Joseph MD, Catherine R. MD, PhD,