Oral Phenylephrine HCl for Nasal Congestion in Seasonal Allergic Rhinitis: A Randomized, Open-label, Placebo-controlled Study

Article ID	Journal	Published Year	Pages	File Type
6068681	The Journal of Allergy and Clinical Immunology: In Practice	2015	7 Pages	PDF

Abstract

PE HCl, at doses of up to 40 mg every 4 hours, is not significantly better than placebo at relieving nasal congestion in adults with SAR. The phenylephrine section of the Food and Drug Administration monograph on over-the-counter cold, cough, allergy, bronchodilator, and antiasthmatic products should be revised accordingly.

Keywords

SBP FDA MAO PDE OTC Pseudoephedrine SAR TEAE ITT over the counter Allergic rhinitis Food and Drug Administration Heart rate adverse event treatment-emergent adverse event systolic blood pressure Blood pressure Seasonal allergic rhinitis Phenylephrine hydrochloride Intent-to-treat monoamine oxidase nasal congestion