| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6078054 | Journal of Investigative Dermatology | 2012 | 4 Pages |
Abstract
Fogo selvagem is an endemic form of pemphigus foliaceus (EPF) found in Brazil. Environmental and genetic factors are thought to contribute to the disease, which is associated with pathogenic IgG4 autoantibodies against the desmosomal cadherin desmoglein 1. In this issue, as an additional framework to understand autoimmune mechanisms in EPF, Flores et al. have investigated whether fogo selvagem patients and healthy individuals from endemic areas develop autoantibody responses against other desmosomal cadherins and E-cadherin.
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Authors
Giovanni Di Zenzo, Giovanna Zambruno, Luca Borradori,