Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6090874 | Clinical Gastroenterology and Hepatology | 2016 | 12 Pages |
Abstract
The development of thrombocytopenia in patients with ALF is associated with the development of MOSF and poor outcome. We speculate that SIRS-induced activation of platelets, yielding microparticles, results in clearance of platelet remnants and subsequent thrombocytopenia.
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Authors
R. Todd Stravitz, Caitlyn Ellerbe, Valerie Durkalski, Adrian Reuben, Ton Lisman, William M. Lee, Acute Liver Failure Study Group Acute Liver Failure Study Group,