| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6090956 | Clinical Gastroenterology and Hepatology | 2015 | 9 Pages |
Abstract
A reduction in BMI of at least 5% is associated with significant decrease in liver fat and volume in patients with biopsy-proven NASH. These data should be considered in assessing effect size in studies of patients with nonalcoholic fatty liver disease or obesity that use MRI-estimated liver fat and volume as end points.
Keywords
NASNAFLDPDFFALTMRSROIASTAspartate aminotransferaseAlanine aminotransferasenonalcoholic steatohepatitisMRINonalcoholic fatty liver diseaseBiomarkerMagnetic resonance imagingSteatosisbody mass indexBMImagnetic resonance spectroscopynoninvasiveregion of interestNonalcoholic fatty liver disease activity scoreNash Response to treatmentproton density fat fraction
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Authors
Niraj S. Patel, Iliana Doycheva, Michael R. Peterson, Jonathan Hooker, Tatiana Kisselva, Bernd Schnabl, Ekihiro Seki, Claude B. Sirlin, Rohit Loomba,