| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6091364 | Clinical Gastroenterology and Hepatology | 2014 | 13 Pages |
Abstract
In patients with Parkinson's disease, dopaminergic medications such as levodopa can negatively affect swallowing. The increased cortical excitability observed in dysphagic patients after they begin taking levodopa likely results from compensatory mechanisms, perhaps secondary to subcortical disease, because we observed associated inhibition of brainstem reflexes in patients with affected swallowing on medication. UK clinical trials registration no., 9882.
Keywords
pmepTMSCoGSDQVFSQOLNSIQuality of lifel-3,4-dihydroxyphenylalaninemotor thresholdEMGelectromyographyParkinson's diseaseTranscranial magnetic stimulationanalysis of varianceANOVANeurodegenerationCompensationNervous systemSionEuclidian distanceMotor cortexlevodopacenter of gravityBrainHospital Anxiety and Depression ScaleHADSVideofluoroscopy
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Authors
Emilia Michou, Shaheen Hamdy, Mary Harris, Adil Vania, Jeremy Dick, Mark Kellett, John Rothwell,