| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6091475 | Clinical Gastroenterology and Hepatology | 2014 | 24 Pages |
Abstract
On the basis of an analysis of 2 large clinical trials (FUSION and NEUTRINO), patient outcome and productivity are more negatively affected by the inclusion of pegylated interferon in treatment than by interferon-free regimens. Patients with sustained virologic responses 12Â weeks after treatment had significant improvements in PROs in both studies.
Keywords
SF-36FACIT-FSVRCH-CSofosbuvirMCIDSOFCLDQ-HCVWPAIHRQLFunctional Assessment of Chronic Illness Therapy-FatigueEWBFWBPWBSWBQuality of lifeWork productivityLiver diseaseMinimal Clinically Important DifferenceEmotional Well-BeingSocial well-beingPhysical well-beingSystemicEmotionalShort Form-36patient-reported outcomePROWorryHepatitis Cchronic hepatitis CHepatitis C virusHCVSustained virologic responseHealth-related quality of life
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Authors
Zobair M. Younossi, Maria Stepanova, Linda Henry, Edward Gane, Ira M. Jacobson, Eric Lawitz, David Nelson, Lynn Gerber, Fatema Nader, Sharon Hunt,