Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6091841 | Gastroenterology | 2016 | 110 Pages |
Abstract
In comparing gene expression profiles between liver tissues from different mouse models of NAFLD and patients with different stages of NAFLD, we found very little overlap. Our data set is available for studies of pathways that contribute to the development of NASH and NAFLD and selection of the most applicable mouse models (http://www.nash-profiler.com).
Keywords
NASmethionine- and choline-deficient dietNAFLDMouse Genome InformaticsMGIMCDGSEASTZHFDHUGO Gene Nomenclature CommitteeHGNCFDRNCBIHCCPCAnonalcoholic steatohepatitisStreptozocinNonalcoholic fatty liver diseasePrinciple component analysisGene Set Enrichment AnalysisTranscriptomeSteatosishigh-fat dietphosphatase and tensin homologue deleted on chromosome 10National Center for Biotechnology InformationComparativefalse discovery rateNonalcoholic fatty liver disease activity scoreNash PtenHepatocellular carcinoma
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Authors
Andreas Teufel, Timo Itzel, Wiebke Erhart, Mario Brosch, Xiao Yu Wang, Yong Ook Kim, Witigo von Schönfels, Alexander Herrmann, Stefan Brückner, Felix Stickel, Jean-François Dufour, Triantafyllos Chavakis, Claus Hellerbrand, Rainer Spang,