Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6092350 | Gastroenterology | 2015 | 29 Pages |
Abstract
After 55 years of age, subjects with 1 FDR with CRC had only a modest increase in risk for CRC incidence and death; age of onset in the FDR was not significantly associated with risk. Individuals with â¥2 FDRs with CRC had continued increased risk in older age. Guidelines and clinical practice for subjects with a family history of CRC should be modified to align CRC testing to risk. ClinicalTrials.gov number, NCT00002540.
Keywords
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Authors
Robert E. Schoen, Anthony Razzak, Kelly J. Yu, Sonja I. Berndt, Kevin Firl, Thomas L. Riley, Paul F. Pinsky,