Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6092584 | Gastroenterology | 2016 | 32 Pages |
Abstract
TM6SF2 regulates cholesterol metabolism in mice and might be a therapeutic target for cardiovascular disease.
Keywords
TNFtransmembrane 6 superfamily member 2TM6SF2ABCG5LDL-CMCP-1mRNAHFDHDLALBhigh-density lipoproteinmessenger RNAAlbuminLipid disordernonalcoholic steatohepatitiscardiovascular diseasetriglycerideGene regulationCVDhigh-fat dietendoplasmic reticulumtumor necrosis factorknockoutNash polymerase chain reactionPCRbody weightliver weightmonocyte chemoattractant protein-1Membrane proteinsTranslational researchtotal cholesterolLow-density lipoprotein cholesterol
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Authors
Yanbo Fan, Haocheng Lu, Yanhong Guo, Tianqing Zhu, Minerva T. Garcia-Barrio, Zhisheng Jiang, Cristen J. Willer, Jifeng Zhang, Y. Eugene Chen,