Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy

Article ID	Journal	Published Year	Pages	File Type
6093180	Gastroenterology	2015	42 Pages	PDF

Abstract

We developed and validated scoring system (the GLOBE score) to predict transplant-free survival of ursodeoxycholic acidâtreated patients with PBC. This score might be used to select strategies for treatment and care.

Keywords

UDCA ALT ULN PBC NRI AST Aspartate aminotransferase Alanine aminotransferase Ursodeoxycholic acid Net reclassification improvement autoimmune liver disease Upper limit of normal Primary biliary cirrhosis Predictive factor confidence interval prognosis cholestasis

Related Topics

Health Sciences Medicine and Dentistry Gastroenterology

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Development and Validation of a Scoring System to Predict Outcomes of Patients With Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy

Authors

Willem J. Lammers, Gideon M. Hirschfield, Christophe Corpechot, Frederik Nevens, Keith D. Lindor, Harry L.A. Janssen, Annarosa Floreani, Cyriel Y. Ponsioen, Marlyn J. Mayo, Pietro Invernizzi, Pier M. Battezzati, Albert Parés, Andrew K. Burroughs,