| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6093183 | Gastroenterology | 2015 | 73 Pages |
Abstract
Nuclear localization of DNAJB6 is associated with longer survival times of patients with ESCC. DNAJB6a reduces AKT signaling, and DNAJB6 expression in cancer cells reduces their proliferation and growth of xenograft tumors in mice. DNAJB6a might be developed as a biomarker for progression of ESCC.
Keywords
NLSDNAJB6nESHPDIGFNIREACTMAPP2AESCCHspv-akt murine thymoma viral oncogene homolog 1Esophageal adenocarcinomaAktTumor suppressornuclear export signalnuclear localization signalconfidence intervalInsulin-like growth factorTissue microarrayNear-infraredhazard ratioPrognostic markerwild typeSignal transductionHeat shock proteinprotein phosphatase 2AEsophageal squamous cell carcinoma
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Authors
Valen Zhuoyou Yu, Victor Chun-Lam Wong, Wei Dai, Josephine Mun-Yee Ko, Alfred King-Yin Lam, Kwok Wah Chan, Rajeev S. Samant, Hong Lok Lung, Wai Ho Shuen, Simon Law, Yuen Piu Chan, Nikki Pui-Yue Lee, Daniel King Hung Tong, Tsz Ting Law, Victor Ho-Fun Lee,