Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6093352 | Gastroenterology | 2015 | 62 Pages |
Abstract
LRIG1 regulates the postnatal development of ICC-DMP and ICC-SMP from smooth muscle progenitors in mice. Slowed small intestinal transit observed in Lrig1-null mice may be due, at least in part, to loss of the ICC-DMP population.
Keywords
PBSLRIG1ICCanoctamin-1DMPANO1DAPINK1RYFPRFPPDGFRA4',6-diamidino-2-phenylindolesmooth muscle actindeep muscular plexussubmucosal plexusIntestinal transitSMPSMADevelopmentinterstitial cells of CajalPhosphate-buffered salinewild-typeyellow fluorescent proteinred fluorescent proteinNeurokinin 1 receptorplatelet-derived growth factor receptor α
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Authors
Jumpei Kondo, Anne E. Powell, Yang Wang, Melissa A. Musser, E. Michelle Southard-Smith, Jeffrey L. Franklin, Robert J. Coffey,