Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6093766 | Gastroenterology | 2014 | 47 Pages |
Abstract
Activation of the VDR represses hepatic SHP to increase levels of mouse and human CYP7A1 and reduce cholesterol.
Keywords
mRNALRH-1RXRαFGF15VDRECDCALDL-CHDL-C1α,25-dihydroxyvitamin D3farnesoid X receptormessenger RNAAsbtChenodeoxycholic acidBile acidchromatin immunoprecipitationTranscriptional regulationEMSA یا electrophoretic mobility shift assay high-density lipoprotein cholesterolCHiPLiverLow-density lipoprotein cholesterol
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Authors
Edwin C.Y. Chow, Lilia Magomedova, Holly P. Quach, Rucha Patel, Matthew R. Durk, Jianghong Fan, Han-Joo Maeng, Kamdi Irondi, Sayeepriyadarshini Anakk, David D. Moore, Carolyn L. Cummins, K. Sandy Pang,