Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6093778 | Gastroenterology | 2014 | 19 Pages |
Abstract
In 2 mouse models of acute pancreatitis, intracellular HMGB1 appeared to prevent nuclear catastrophe and release of inflammatory nucleosomes to block inflammation. These findings indicate a role for the innate immune response in tissue damage.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Rui Kang, Qiuhong Zhang, Wen Hou, Zhenwen Yan, Ruochan Chen, Jillian Bonaroti, Preeti Bansal, Timothy R. Billiar, Allan Tsung, Qingde Wang, David L. Bartlett, David C. Whitcomb, Eugene B. Chang, Xiaorong Zhu, Haichao Wang, Ben Lu, Kevin J. Tracey,