Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6094463 | Gastroenterology | 2013 | 19 Pages |
Abstract
In analyses of gastric cancer cell lines, human tissue samples, and mouse models, we found AURKA to be up-regulated during chronic inflammation to promote activation of NF-κB and tumorigenesis. AURKA inhibitors might be developed as therapeutic agents for gastric cancer.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Ahmed Katsha, Mohammed Soutto, Vikas Sehdev, Dunfa Peng, M. Kay Washington, M. Blanca Piazuelo, Mohammed N. Tantawy, H. Charles Manning, Pengcheng Lu, Yu Shyr, Jeffrey Ecsedy, Abbes Belkhiri, Wael El-Rifai,