| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6094614 | Gastroenterology | 2014 | 14 Pages |
Abstract
IFN-induced expression of MHC class I is attenuated in HCV-infected cells by activation of PKR, which reduces the effector functions of HCV-specific CD8+ T cells. This appears to be an important mechanism by which HCV circumvents antiviral adaptive immune responses.
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Authors
Wonseok Kang, Pil Soo Sung, Su-Hyung Park, Sarah Yoon, Dong-Yeop Chang, Seungtaek Kim, Kwang Hyub Han, Ja Kyung Kim, Barbara Rehermann, Yong-Joon Chwae, Eui-Cheol Shin,