Article ID Journal Published Year Pages File Type
6094615 Gastroenterology 2014 44 Pages PDF
Abstract
Cleavage at the NS2/3 junction is a rate-limiting step in replication of particular HCV isolates and determines their sensitivity to CypA inhibitors. These drugs target de novo formation of the membranous web and RNA replication.
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Health Sciences Medicine and Dentistry Gastroenterology
Preview
Inhibition of HCV Replication by Cyclophilin Antagonists Is Linked to Replication Fitness and Occurs by Inhibition of Membranous Web Formation
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