| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6094852 | Gastroenterology | 2013 | 10 Pages |
Abstract
Based on studies of Duoxa-/- mice, the DUOX enzyme complex prevents gastric colonization by H felis and the inflammatory response. These findings indicate the nonredundant function of epithelial production of H2O2 in restricting microbial colonization.
Keywords
HRPdual oxidasesKrebs–Ringer–HEPES bufferDUOXAKRHDUOXNADPHmRNAFBSPBSmessenger RNAAdenosine TriphosphateATPGlucose oxidaseMucosal immunityGoxGastrointestinaldual oxidasefetal bovine serumPhosphate-buffered salineMouse modelHorseradish peroxidasereduced nicotinamide adenine dinucleotide phosphateGastritis
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Authors
Helmut Grasberger, Mohamad El-Zaatari, Duyen T. Dang, Juanita L. Merchant,