| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6095135 | Gastroenterology | 2013 | 11 Pages |
Abstract
EPAS1 is a transcription factor that activates mediators of inflammation, such as tumor necrosis factorâα, in the intestinal epithelium and promotes development of colitis in mice.
Keywords
NF-κBoxygen-dependent degradationDSSTNFdimethyloxaloylglycineIBDMyc-associated zinc finger proteinEPAS1DMOGPHDHIFOxygeninterleukinCrohn's diseaseInflammatory bowel diseaseDextran sulfate sodiumHypoxia-inducible factortumor necrosis factornuclear factor κBODDMouse modelwild typeProlyl hydroxylaseMazUlcerative colitis
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Authors
Xiang Xue, Sadeesh Ramakrishnan, Erik Anderson, Matthew Taylor, Ellen M. Zimmermann, Jason R. Spence, Sha Huang, Joel K. Greenson, Yatrik M. Shah,