| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6095138 | Gastroenterology | 2013 | 30 Pages |
Abstract
miR-124 appears to regulate the expression of STAT3. Reduced levels of miR-124 in colon tissues of children with active UC appear to increase expression and activity of STAT3, which could promote inflammation and the pathogenesis of UC in children.
Keywords
IL6IBDMIRDSSmRNAMMP9p-STAT3BclXLSTAT35-Aza-2′-deoxycytidine5-Azamessenger RNALet-7interleukinCrohn's diseaseInflammatory bowel diseaseELISAEnzyme-linked immunosorbent assayGene regulationVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)phosphorylated STAT3matrix metallopeptidase 9signal transducer and activator of transcription 3MicroRNAknockoutpolymerase chain reactionPCRUlcerative colitis
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Georgios Koukos, Christos Polytarchou, Jess L. Kaplan, Alessio Morley-Fletcher, Beatriz Gras-Miralles, Efi Kokkotou, Mariah Baril-Dore, Charalabos Pothoulakis, Harland S. Winter, Dimitrios Iliopoulos,