| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6095244 | Gastroenterology | 2014 | 42 Pages |
Abstract
In a genome-wide association study, we associated AIH type 1 with variants in the major histocompatibility complex region, and identified variants of SH2B3and CARD10 as likely risk factors. These findings support a complex genetic basis for AIH pathogenesis and indicate that part of the genetic susceptibility overlaps with that for other immune-mediated liver diseases.
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Authors
Ynto S. de Boer, Nicole M.F. van Gerven, Antonie Zwiers, Bart J. Verwer, Bart van Hoek, Karel J. van Erpecum, Ulrich Beuers, Henk R. van Buuren, Joost P.H. Drenth, Jannie W. den Ouden, Robert C. Verdonk, Ger H. Koek, Johannes T. Brouwer,