Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6095248 | Gastroenterology | 2014 | 38 Pages |
Abstract
DAAs that target NS5A rapidly inhibit intracellular assembly of genotype 1a virions. They also inhibit formation of functional replicase complexes, but have no activity against preformed replicase, thereby resulting in slow shut-off of viral RNA synthesis.
Keywords
Related Topics
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Gastroenterology
Authors
David R. McGivern, Takahiro Masaki, Sara Williford, Paul Ingravallo, Zongdi Feng, Frederick Lahser, Ernest Asante-Appiah, Petra Neddermann, Raffaele De Francesco, Anita Y. Howe, Stanley M. Lemon,