| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6095253 | Gastroenterology | 2014 | 64 Pages |
Abstract
Loss of SMAD4 in PDAC cells leads to reduced levels of miR-494, increased levels of FOXM1, and nuclear localization of β-catenin. miR-494 might be developed as a prognostic marker for patients with PDAC or a therapeutic target.
Keywords
FOXM1qPCRmRNALMDTGFmessenger RNAPancreatic ductal adenocarcinomaPDAC یا pancreatic ductal adenocarcinomaTOPtransforming growth factorGene regulationforkhead box M1Pancreatic cancerUTR یا untranslated regions untranslated regionMicroRNAMiRNApancreatic intraepithelial neoplasiaSignal transductionpolymerase chain reactionquantitative polymerase chain reactionPCRPanINTumor progression
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Authors
Lei Li, Zhaoshen Li, Xiangyu Kong, Dacheng Xie, Zhiliang Jia, Weihua Jiang, Jiujie Cui, Yiqi Du, Daoyan Wei, Suyun Huang, Keping Xie,