| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6095694 | Gastroenterology | 2011 | 10 Pages |
Abstract
CSCs are present in NETs, as shown by in vitro sphere formation and in vivo tumorigenicity assays. Src was activated in N-CSCs and represents a potential therapeutic target in gastrointestinal NETs.
Keywords
ALDHCSC4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidinePBSFACSDOPCPP2DMEMmTOR1,2-dioleoyl-sn-glycero-3-phosphatidylcholine3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromideDMSODulbecco's modified Eagle MediumMTTNETsshort interfering RNAsiRNAneuroendocrine tumorsCarcinoid tumorsfluorescence-activated cell sortingDimethyl sulfoxidecancer stem cellCancer stem cellsPhosphate-buffered salinemammalian target of rapamycin
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Authors
Puja Gaur, Eric L. Sceusi, Shaija Samuel, Ling Xia, Fan Fan, Yunfei Zhou, Jia Lu, Federico Tozzi, Gabriel Lopez-Berestein, Pablo Vivas-Mejia, Asif Rashid, Jason B. Fleming, Eddie K. Abdalla, Steven A. Curley, Jean-Nicolas Vauthey, Anil K. Sood,