| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6095726 | Gastroenterology | 2011 | 11 Pages |
Abstract
Reduced levels of RA appear to induce IECs to up-regulate synthesis of RA. RA supplementation attenuates ileitis through its effects on CD103+ DCs, Tregs, and Th17 cells. RA supplementation might offer therapeutic benefit in Crohn's disease.
Keywords
TNFFOXP3TregMLNTGFT-helperinflammationinterleukinInflammatory bowel diseasetransforming growth factorToleranceforkhead box P3RALDHRetinoic acidRegulatory T cellDendritic cellintestinal epithelial celltumor necrosis factorLamina propriawild-typepolymerase chain reactionPCRImmune responseIECmesenteric lymph node
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Authors
Colm B. Collins, Carol M. Aherne, Douglas Kominsky, Eóin N. McNamee, Matthew D.P. Lebsack, Holger Eltzschig, Paul Jedlicka, Jesús Rivera-Nieves,