Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6096021 | Gastroenterology | 2012 | 14 Pages |
Abstract
The transcription factor Cdx2 activates expression of the protocadherin Mucdhl, which interacts with β-catenin and regulates activities of intestinal cells. Loss of Cdx2 expression in colon cancer cells might reduce expression of Mucdhl and thereby lead to tumor formation.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Gastroenterology
Authors
Isabelle Hinkel, Isabelle Duluc, Elisabeth Martin, Dominique Guenot, Jean-Noel Freund, Isabelle Gross,