| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6096195 | Gastroenterology | 2013 | 18 Pages |
Abstract
Exposure of mice to stress inhibits NLRP6 and alters the composition of the gut microbiota, leading to intestinal inflammation. These findings might explain the benefits of probiotics for patients with stress-associated gastrointestinal disorders.
Keywords
PBSLPMCperoxisome proliferator–activated receptor γNlrpIBSDSSCRHFITCPPAR-γinterleukinWASTreatmentlamina propria mononuclear cellirritable bowel syndromeDextran sulfate sodiumfluorescein isothiocyanateLamina propriaPhosphate-buffered salineMouse modelcorticotropin-releasing hormoneInflammatory response
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Authors
Yundong Sun, Min Zhang, Chun-Chia Chen, Merritt III, Xia Sun, Mohamad El-Zaatari, Gary B. Huffnagle, Vincent B. Young, Jiajie Zhang, Soon-Cheol Hong, Yu-Ming Chang, Deborah L. Gumucio, Chung Owyang, John Y. Kao,