| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6096416 | Gastroenterology | 2010 | 24 Pages |
Abstract
KLF8 promotes HCC cell proliferation and invasion, inhibits apoptosis, and induces the epithelial-to-mesenchymal transition. KLF8 up-regulation might be used to indicate poor prognosis or early recurrence of cancer in patients who have had surgery for HCC.
Keywords
BCLCTACETTRHBsAgALTqRT-PCRTNMRT-PCRFAKTgf-αshRNAMMPKLFsKrüppel-like factorsIRF7Metastatic liver cancerGGTTMAsPBScDNAtranscatheter arterial chemoembolizationComplementary DNAHCCMAPKRNA interferenceSmall interfering RNARNAismall hairpin RNAsiRNAα-fetoproteinγ-glutamyl transpeptidaseAlanine aminotransferaseHepatitis B surface antigenchromatin immunoprecipitationoverall survivaltransforming growth factor αsmall interference RNAAFPtumor-node-metastasisEMTtime to recurrenceLiver cancerInterferon regulatory factor 7matrix metalloproteinasePhosphate-buffered salineTumor microenvironmenttissue microarraysHBVreverse transcription polymerase chain reactionquantitative real-time reverse transcription polymerase chain reactionhepatitis B virusmitogen-activated protein kinaseCHiPHepatocellular carcinomaBarcelona Clinic Liver Cancerfocal adhesion kinaseepithelial-to-mesenchymal transition
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Authors
Jia-Chu Li, Xin-Rong Yang, Hai-Xiang Sun, Yang Xu, Jian Zhou, Shuang-Jian Qiu, Ai-Wu Ke, Yue-Hong Cui, Zhi-Jun Wang, Wei-Min Wang, Kang-Da Liu, Jia Fan,