| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6096565 | Gastroenterology | 2010 | 12 Pages |
Abstract
PIR-B negatively regulates macrophage functions in response to pathogenic bacteria and chronic intestinal inflammatory responses. Inhibitory receptors such as PIR-B might be used as therapeutic targets for treatment of patients with IBD.
Keywords
NF-κBITIMILTc-Jun-N-terminal kinaseIBDSHPERKeGFPDSSJnkLPSMAPKimmunoglobulin interleukinLIRPirimmunoglobulin-like transcriptdextran sodium sulfatenuclear factor κBLamina proprialipopolysaccharideMacrophagesImmunoreceptor tyrosine-based inhibitory motifenhanced green fluorescent proteinmitogen-activated protein kinaseExtracellular signal–regulated kinaseleukocyte immunoglobulin-like receptorInhibitory receptors
Related Topics
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Gastroenterology
Authors
Ariel Munitz, Eric T. Cole, Amanda Beichler, Katherine Groschwitz, Richard Ahrens, Kris Steinbrecher, Tara Willson, Xiaonan Han, Lee Denson, Marc E. Rothenberg, Simon P. Hogan,