Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6096736 | Gastroenterology | 2011 | 12 Pages |
Abstract
Parenteral immunization with a Helicobacter vaccine using a novel mycobacterial adjuvant induces protective immunity against H pylori that is mediated by Th1 and Th17 cells. Tolerance mechanisms mediated by dendritic cells and regulatory T cells impair H pylori clearance and must be overcome to improve immunity.
Keywords
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Gastroenterology
Authors
Iris Hitzler, Mathias Oertli, Burkhard Becher, Else Marie Agger, Anne Müller,