Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6096760 | Gastroenterology | 2011 | 10 Pages |
Abstract
The resistance of colorectal tumors to irinotecan requires the cooperative action of tumor-initiating ALDHhigh/ABCB1negative cells and their differentiated, drug-expelling, ALDHlow/ABCB1positive daughter cells.
Keywords
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Authors
Benjamin L. Emmink, Winan J. Van Houdt, Robert G. Vries, Frederik J.H. Hoogwater, Klaas M. Govaert, Andre Verheem, Maarten W. Nijkamp, Ernst J.A. Steller, Connie R. Jimenez, Hans Clevers, Inne H.M. Borel Rinkes, Onno Kranenburg,