| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 6106948 | Journal of Hepatology | 2009 | 11 Pages |
Abstract
Our data support the relevance of EGFR-mediated signalling in the modulation of cytokine-activated pathways. We have identified AR as a key regulator of hepatic APP gene expression during inflammation and liver regeneration.
Keywords
α1-antichymotrypsinEREGEpiregulinTNFMEK1SHP2SOCSSAAHB-EGFEGFRTGFActDERKOSMBTCLPSAPPshort interfering RNAsiRNASTATamphiregulinAproncostatin Mactinomycin Dchromatin immunoprecipitationinterleukinLiver regenerationBetacellulintransforming growth factorSAA, Serum amyloid Asuppressor of cytokine signallingtumour necrosis factorHeparin-binding EGF-like growth factorlipopolysaccharideSignal transducer and activator of transcriptionPartial hepatectomyAcute-phase reactionAcute-phase proteinAcute-phase proteinsJAKCHiPextracellular regulated kinaseEpidermal growth factor receptorjanus-activated kinase
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Authors
Ana Pardo-Saganta, Maria Ujue Latasa, Josefa Castillo, Laura Alvarez-Asiain, MarÃa J. PerugorrÃa, Pablo Sarobe, Carlos M. Rodriguez-Ortigosa, Jesús Prieto, Carmen Berasain, Mónica SantamarÃa, MatÃas A. Avila,