Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6108058 | Journal of Hepatology | 2009 | 9 Pages |
Abstract
In IDV treatment the risk of severe hyperbilirubinemia is associated with genetic variants of the UGT1A3 and UGT1A7 genes in addition to Gilbert's syndrome (UGT1A1*28). This haplotype is a useful predictor of protease inhibitor-induced side effects.
Keywords
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Authors
Tim O. Lankisch, Georg Behrens, Ursula Ehmer, Ulrike Möbius, Juergen Rockstroh, Michael Wehmeier, Sandra Kalthoff, Nicole Freiberg, Michael P. Manns, Reinhold E. Schmidt, Christian P. Strassburg,