Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6108622 | Journal of Hepatology | 2009 | 12 Pages |
Abstract
The establishment of viral persistence in the special patient group of dialysis patients is due to a failure of the adaptive immune system, as shown by the absence of significant T-cell and antibody responses, as well as viral variability.
Keywords
HVR1Th1HCVppPBMCIFN-gammaGFPNS3CD4TNF-alphaCD8ALTAlanine aminotransferaseNeutralizing antibodiesHuman leukocyte antigenHLAenzyme linked immuno sorbent assayribonucleic acidRNAstandard deviationinterferon-gammaELISAtumor necrosis factor-alphaDialysisperipheral blood mononuclear cellsT-cellsHypervariable region 1Acute hepatitis CHCVHepatitis C viruspolymerase chain reactionPCRImmune responsegreen fluorescent protein
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Authors
Lukas Weseslindtner, Christoph Neumann-Haefelin, Sergei Viazov, Anita Haberstroh, Josef Kletzmayr, Judith H. Aberle, Joerg Timm, Stefan R. Ross, Renate Klauser-Braun, Thomas F. Baumert, Michael Roggendorf, Robert Thimme, Heidemarie Holzmann,