Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6108845 | Journal of Hepatology | 2009 | 10 Pages |
Abstract
In chronic HCV infection, steatosis up-regulates hepatocyte CD95/Fas and thus increases apoptosis, which facilitates inflammation and fibrosis. The physiologic countermeasure of adiponectin up-regulation may offer clues for future therapeutic intervention.
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Authors
Inga Wedemeyer, Lars P. Bechmann, Margarethe Odenthal, Christoph Jochum, Guido Marquitan, Uta Drebber, Guido Gerken, Robert K. Gieseler, Hans P. Dienes, Ali Canbay,