Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
6109105 | Journal of Hepatology | 2008 | 9 Pages |
Abstract
1b-NS5As exert higher magnitudes of IFN antagonism than do 2a-NS5As. The V3 and the C-terminus regions are responsible for the differential anti-IFN effects. This phenomenon may partly explain the genotype-linked differences in the response of HCV to IFN treatment.
Keywords
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Authors
Ya-Hui Tsai, Wan-Fen Kuang, Tsai-Yi Lu, Jia-Horng Kao, Ming-Yang Lai, Chun-Jen Liu, Pei-Jer Chen, Lih-Hwa Hwang,